High-risk medicines guide
🔒 Pro featureA deep, chapter-by-chapter guide to the medicines most likely to cause serious harm if used in error, a favourite area of the GPhC exam. 16chapters covering each drug’s key risks, counselling, monitoring, interactions and signs of toxicity.
The high-risk medicines guide is part of PassPharm Pro. Chapter 1 is free to read.
See Pro1What makes a medicine high-riskFreeWhy some medicines carry a much higher risk of serious harm.2🔒 WarfarinINR targets, interactions, reversal and counselling.3🔒 DOACsApixaban, rivaroxaban, dabigatran and edoxaban.4🔒 Heparins and LMWHUFH versus LMWH, monitoring, reversal and HIT.5🔒 InsulinInsulin types, units, hypoglycaemia and storage.6🔒 OpioidsRespiratory depression, conversion, patches and naloxone.7🔒 MethotrexateWeekly dosing, folic acid, monitoring and interactions.8🔒 LithiumNarrow index, level monitoring, toxicity and precipitants.9🔒 AntiepilepticsValproate, phenytoin, carbamazepine and lamotrigine.10🔒 DigoxinToxicity, potassium, levels and interactions.11🔒 AmiodaroneLong half-life, multi-organ monitoring and interactions.12🔒 Aminoglycosides and vancomycinNephrotoxicity, ototoxicity and level monitoring.13🔒 NSAIDsGI, renal, cardiovascular and asthma risks.14🔒 ImmunosuppressantsCiclosporin, tacrolimus and azathioprine.15🔒 CorticosteroidsAdrenal suppression, steroid card and sick-day rules.16🔒 ClozapineAgranulocytosis monitoring, smoking and missed doses.
⚠️ Always check current guidance
This guide is revision material to help you learn and apply the principles. Doses, targets and monitoring change over time, so the current BNF, NICE guidance and the manufacturer’s summary of product characteristics always take precedence.