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Choice of antihypertensive and cardiovascular drug

For each patient below, select the single most appropriate drug from the list of options. Each option may be used once, more than once, or not at all.

Options

  1. AAmlodipine
  2. BRamipril
  3. CBisoprolol
  4. DSpironolactone
  5. EDoxazosin
  6. FBendroflumethiazide
  7. GFurosemide
  8. HLosartan

1.A 50-year-old man of black African origin is newly diagnosed with hypertension and has no diabetes. He needs a first-line antihypertensive.

2.A 45-year-old man of white European origin with newly diagnosed hypertension and no diabetes needs first-line treatment.

3.A patient with resistant hypertension is already on an ACE inhibitor, a calcium channel blocker, and a thiazide-like diuretic. Their potassium is 4.2 mmol/L and a fourth drug is needed.

4.A patient with heart failure has peripheral oedema and breathlessness from fluid overload needing symptomatic relief.

5.A patient develops a persistent dry cough soon after starting their antihypertensive and needs a suitable switch.

6.A man has both hypertension and stable angina, and would benefit from a drug that also reduces his anginal symptoms.

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